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Although many viruses can cause meningitis, the most common viral cause is ______.


A) enterovirus
B) arbovirus
C) herpes simplex
D) arenavirus
E) cytomegalovirus

F) C) and D)
G) D) and E)

Correct Answer

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Which of the following is not true of meningoencephalitis?


A) The condition involves infection of both the brain and meninges.
B) The mode of transmission is via respiratory droplets.
C) The treatment for primary amoebic meningoencephalitis (PAM) is mostly ineffective.
D) The causative organisms are Naegleria fowleri and Acanthamoeba.

E) C) and D)
F) A) and D)

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Up to 50% of persons who survived polio as children will suffer from post-polio syndrome later in life.

A) True
B) False

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Cryptococcus neoformans is a ______.


A) gram-negative bacterium
B) fungus
C) gram-positive bacterium
D) prion

E) A) and B)
F) All of the above

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Prions can be destroyed by autoclaving.

A) True
B) False

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Meningococci initially colonize the ______.


A) oral mucosa
B) lacrimal ducts
C) nasopharynx
D) Eustachian tube

E) B) and C)
F) A) and C)

Correct Answer

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Which of the following diseases exhibits the highest mortality rate?


A) La Crosse encephalitis
B) Jamestown Canyon encephalitis
C) Eastern equine encephalitis
D) West Nile encephalitis

E) C) and D)
F) None of the above

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C

Subacute sclerosing panencephalitis is caused by a prion.

A) True
B) False

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False

Which of the following is not a prion disease?


A) Scrapie
B) Bovine spongiform encephalopathy
C) Creutzfeldt-Jacob disease
D) Subacute sclerosing panencephalitis

E) A) and D)
F) A) and C)

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Although prion infectious agents are more closely related to viruses than any other kind of infectious agents, there are still some major differences between the two. Which statement describes a major difference?


A) Viral infections can always be treated and cured, whereas prion diseases cannot.
B) Viruses can be transmitted by animal to human or human to human, but prions are always human to human transmission.
C) Prions are not destroyed by heat, but viruses can be inactivated by heat.
D) Viruses do not contain protein, whereas prions do.

E) All of the above
F) A) and B)

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The best defense against arboviruses is ______.


A) vector control
B) prophylactic rifampin
C) vaccination
D) prompt treatment with acyclovir

E) B) and C)
F) None of the above

Correct Answer

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Cerebrospinal ?uid is found in the ______.


A) pia mater
B) dura mater
C) subarachnoid space
D) arachnoid mater
E) All of the choices are correct.

F) A) and B)
G) C) and E)

Correct Answer

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In rabies, spasms of muscles for swallowing lead to a fear of water.

A) True
B) False

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Neonatal meningitis is most commonly transmitted by ______.


A) exposure from other infants
B) hospital personnel
C) exposure in the birth canal
D) transplacental infection
E) breastfeeding

F) None of the above
G) B) and D)

Correct Answer

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C

Which of the following statements about rabies is incorrect?


A) Wild populations of bats, skunks, raccoons, cats, and canines are primary reservoirs.
B) The average incubation period in human is one week.
C) Rabies is a zoonotic disease.
D) Transmission can involve bites, scratches, and inhalation.
E) Symptoms include anxiety, agitation, muscle spasms, convulsions, and paralysis.

F) B) and E)
G) A) and D)

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Treatment of an animal bite for possible rabies includes _______.


A) debridement
B) washing the bite with soap or detergent
C) infusing the wound with human rabies immune globulin (HRIG)
D) postexposure vaccination
E) All of the choices are correct.

F) B) and D)
G) C) and E)

Correct Answer

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Which of the following is not a causative agent of acute encephalitis?


A) Toxoplasma gondii
B) Varicella-zoster virus
C) Arbovirus
D) JC virus
E) Herpes simplex virus

F) A) and B)
G) B) and E)

Correct Answer

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Viral meningitis normally requires aggressive antiviral treatment.

A) True
B) False

Correct Answer

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What organism is the main reservoir and host for Toxoplasma gondii?


A) Dog
B) Mosquito
C) Cat
D) Raccoon
E) Mouse

F) C) and D)
G) B) and E)

Correct Answer

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Which of the following statements regarding poliomyelitis is incorrect?


A) It can be asymptomatic or mild with headache, sore throat, fever, and nausea.
B) If the virus enters the central nervous system, motor neurons can be infected and destroyed.
C) It is caused by poliovirus (genus Enterovirus) .
D) Summer outbreaks in the U.S. have been increasing in frequency.
E) The virus is transmitted by contaminated water.

F) B) and E)
G) A) and C)

Correct Answer

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