Question 1

Nitroprusside administration may lead to the accumulation of which toxic compound in the body?

Accepted Answer

A)   formaldehyde
B)   bromine
C)   cyanide
D)   nitrobenzene
E)   superoxideF) A) and B)
G) D) and E)

Question 2

A patient with a hypertensive emergency is given an intravenous infusion of a drug that dilates renal afferent and efferent arterioles and is rapidly metabolized with a half-life of 5 minutes. Which mechanism is responsible for the therapeutic effect of this drug?

Accepted Answer

A)   activation of dopamine D1 receptors
B)   activation of dopamine D2 receptors
C)   blockade of α 1-adrenoceptors
D)   activation of α 2-adrenoceptors
E)   blockade of α 1- and β1-adrenoceptorsF) B) and E)
G) A) and C) A

Question 3

Which enzyme serves as the receptor for aliskiren?

Accepted Answer

A)   angiotensin-converting enzyme
B)   renin
C)   sodium-potassium adenosine triphosphatase
D)   carbonic anhydrase
E)   nitric oxide synthaseF) A) and B)
G) C) and D) B

Question 4

After several months of antihypertensive drug therapy, a patient develops a lupus erythematosus-like syndrome.
Which agent is most likely responsible for this adverse effect?

Accepted Answer

A)   minoxidil
B)   hydrochlorothiazide
C)   captopril
D)   verapamil
E)   hydralazineF) All of the above
G) D) and E) E

Question 5

Which antihypertensive drug is most likely to reduce vascular injury by inhibiting activation of growth factors that cause smooth muscle proliferation and hypertrophy?

Accepted Answer

A)   clonidine
B)   terazosin
C)   atenolol
D)   candesartan
E)   nifedipineF) B) and D)
G) B) and E)

Exam 10: Antihypertensive Drugs

Nitroprusside administration may lead to the accumulation of which toxic compound in the body?

Correct Answer
verified

A patient with a hypertensive emergency is given an intravenous infusion of a drug that dilates renal afferent and efferent arterioles and is rapidly metabolized with a half-life of 5 minutes. Which mechanism is responsible for the therapeutic effect of this drug?

Correct Answer
verified
A

Which enzyme serves as the receptor for aliskiren?

Correct Answer
verified
B

After several months of antihypertensive drug therapy, a patient develops a lupus erythematosus-like syndrome. Which agent is most likely responsible for this adverse effect?

Correct Answer
verified
E

Which antihypertensive drug is most likely to reduce vascular injury by inhibiting activation of growth factors that cause smooth muscle proliferation and hypertrophy?

Correct Answer
verified

Exam 10: Antihypertensive Drugs

Nitroprusside administration may lead to the accumulation of which toxic compound in the body?

Correct AnswerverifiedShow Answer

A patient with a hypertensive emergency is given an intravenous infusion of a drug that dilates renal afferent and efferent arterioles and is rapidly metabolized with a half-life of 5 minutes. Which mechanism is responsible for the therapeutic effect of this drug?

Correct AnswerverifiedA

Which enzyme serves as the receptor for aliskiren?

Correct AnswerverifiedB

After several months of antihypertensive drug therapy, a patient develops a lupus erythematosus-like syndrome. Which agent is most likely responsible for this adverse effect?

Correct AnswerverifiedE

Which antihypertensive drug is most likely to reduce vascular injury by inhibiting activation of growth factors that cause smooth muscle proliferation and hypertrophy?

Correct AnswerverifiedShow Answer

Correct Answer
verified

Correct Answer
verified
A

Correct Answer
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B

Correct Answer
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E

Correct Answer
verified