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Atopy and anaphylaxis are hypersensitivities in the category(ies)


A) type I only.
B) type I and type IV.
C) type IV only.
D) type I, type II, and type III.
E) type I, type II, type III, and type IV.

F) A) and B)
G) None of the above

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An example of a secondary acquired immunodeficiency is


A) AIDS.
B) adenosine deaminase (ADA) deficiency.
C) DiGeorge syndrome.
D) agammaglobulinemia.
E) SCID.

F) C) and D)
G) None of the above

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Once a mother has been sensitized to the Rh factor,


A) all other Rh+ fetuses are at risk.
B) she can be given RhoGAM in future pregnancies to prevent hemolytic disease of the newborn.
C) she can never again have a low risk pregnancy.
D) only future Rh- fetuses are at risk.
E) None of the choices are correct.

F) B) and E)
G) A) and B)

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Epinephrine


A) inhibits the activity of lymphocytes.
B) reverses constriction of airways.
C) is an antihistamine.
D) causes desensitization.

E) A) and B)
F) A) and C)

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B

All of the following are associated with IgE and mast-cell-mediated allergy except ______.


A) allergic asthma
B) systemic lupus erythematosus
C) drug allergies
D) eczema
E) anaphylaxis

F) A) and E)
G) B) and E)

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A second encounter with an allergen that causes a response is called the _____ dose.


A) sensitizing
B) provocative
C) allergic
D) hypersensitivity
E) desensitizing

F) B) and C)
G) A) and E)

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In the theory for allergic desensitization,which immunoglobulin blocks the allergen from binding with IgE?


A) IgD
B) IgE
C) IgA
D) IgM
E) IgG

F) A) and B)
G) A) and D)

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Which event represents the process of releasing chemical mediators?


A)
Histamine acting on smooth muscle
B) Binding of IgE by the Fc region to mast cells and basophils
C)
Prostaglandins causing vasodilation and increased vascular permeability
D) Binding of allergen to adjacent IgE binding sites on mast cells and basophils
E) Degranulation

F) All of the above
G) B) and D)

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The potential for hemolytic disease of the newborn occurs when


A) fetal Rh- cells enter an Rh+ mother.
B) fetal Rh+ cells enter an Rh+ mother.
C) maternal Rh+ cells enter an Rh- fetus.
D) fetal Rh+ cells enter an Rh- mother.
E) maternal Rh- cells enter an Rh+ fetus.

F) A) and B)
G) A) and C)

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What will be the immediate action of an allergen when it enters the body for a second time?


A) Binding of allergen to adjacent IgE binding sites on mast cells and basophils
B) Histamine acts on smooth muscle
C) Prostaglandins cause vasodilation and increased vascular permeability
D) Binding of IgE by the Fc region to mast cells and basophils
E) Degranulation

F) A) and D)
G) A) and C)

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Any heightened immune response resulting in tissue damage is called a(n) ______.


A) immunodeficiency
B) desensitization
C) autoimmune disease
D) hypersensitivity
E) transfusion reaction

F) A) and D)
G) A) and C)

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A seasonal reaction to inhaled allergens is ______.


A) eczema
B) asthma
C) atopic dermatitis
D) anaphylaxis
E) allergic rhinitis

F) C) and D)
G) B) and D)

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All of the following can result in acquired immune deficiency except ______.


A) enzyme deficiency
B) stress
C) malnutrition
D) radiation treatment
E) bacterial infection

F) B) and D)
G) B) and C)

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Which event occurs with the sensitizing dose of allergen?


A) Degranulation
B) Binding of allergen to adjacent IgE binding sites on mast cells and basophils
C) Binding of IgE by the Fc region to mast cells and basophils
D) Histamine acting on smooth muscle
E) Prostaglandins causing vasodilation and increased vascular permeability

F) B) and E)
G) A) and B)

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A systemic,sometimes fatal,reaction with airway obstruction and circulatory collapse is ______.


A) atopic
B) delayed
C) systemic anaphylaxis
D) antibody-mediated
E) T-cell-mediated

F) A) and E)
G) C) and E)

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The leukocyte histamine-release test (LHRT)measures the amount of histamine released from the patient's mast cells and eosinophils when exposed to a specific allergen.

A) True
B) False

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False

Immunopathology is defined as


A) the study of immunodeficiencies.
B) the study of AIDS.
C) the study of autoimmune diseases.
D) the study of immune imbalance, whether hyper- or hypoactivity.

E) A) and D)
F) B) and C)

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SCID is defined by a lack of functional B and T cells which eliminates protection by humoral and cell-mediated immunity.Which of the following is true?


A) A genetic defect disrupts the development of the lymphocytic cell lines.
B) A genetic mutation renders the individual incapable of removing a toxic DNA metabolite from lymphocytes, which ultimately destroys them.
C) Genes coding for B and T cell receptors are mutated so the cells are incapable of binding antigens.
D) Genes that code for interleukin receptors are mutated so the individual's B and T cells do not receive the activation signals, rendering them useless.
E) All of the above describe cases of SCID.

F) A) and B)
G) All of the above

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Which of the following pairs is mismatched?


A) Food allergy - type I hypersensitivity
B) Poison ivy dermatitis - type IV hypersensitivity
C) Transfusion reaction - type II hypersensitivity
D) Hay fever - type IV hypersensitivity
E) Serum sickness - type III hypersensitivity

F) A) and D)
G) All of the above

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High levels of tryptase in the blood is indicative of


A) a viral and/or fungal infection.
B) high levels of degranulating mast cells suggesting an allergic reaction.
C) overuse of dietary supplements.
D) a bacterial infection.

E) A) and B)
F) A) and C)

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B

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