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Please read the clinical scenario, and then answer the question that follow to become familiar with the traditional NCLEX question format. You are on a medical trip to sub-Saharan Africa with a team from your hospital. You are stationed at a well-equipped hospital, in spite of the scant development of the area surrounding the hospital. You meet Raj, a cute 5-year-old boy who runs around barefoot and likes to play in the area ponds to stay cool. He comes into the clinic with a high fever, sore throat, and generalized weakness. His parents are nowhere to be found. Raj says he has been sick for about a week. -Which of the following diseases are you most concerned about,considering the history Raj gave you?


A) meningitis
B) tetanus
C) polio
D) typhoid

E) B) and D)
F) B) and C)

Correct Answer

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Encephalitis caused by arboviruses involves


A) fever,headache,and rash.
B) coma,convulsions,and paralysis in severe cases.
C) myalgia and orbital pain.
D) muscle aches and joint stiffness.
E) All of the choices are correct.

F) A) and B)
G) C) and D)

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What brain defense restricts substances from entering the brain by the vascular system?


A) meninges
B) blood-brain barrier
C) macrophages
D) microglia
E) cranium

F) A) and E)
G) C) and E)

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Cerebrospinal fluid is found in the


A) pia mater.
B) dura mater.
C) subarachnoid space.
D) arachnoid mater.
E) All of the choices are correct.

F) A) and C)
G) A) and B)

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Production of a neurotoxin that prevents acetylcholine release from motor neurons at neuromuscular junctions is a characteristic of


A) Clostridium botulinum.
B) Clostridium perfringens.
C) Clostridium difficile.
D) Clostridium tetani.
E) All of the choices are correct.

F) A) and C)
G) All of the above

Correct Answer

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The normal biota of the CNS consists of


A) Neisseria meningitidis.
B) herpes simplex I.
C) herpes simplex II.
D) Streptococcus agalactiae.
E) The CNS has no normal biota.

F) A) and C)
G) A) and B)

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Which is the exotoxin of botulism?


A) hemolysin
B) tetanospasm
C) peroxidases
D) factor V
E) botulinum

F) B) and D)
G) None of the above

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E

Encephalitis is most commonly caused by a


A) bacteria.
B) protozoan.
C) virus.
D) helminth.
E) All of the choices are correct.

F) None of the above
G) B) and C)

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Subacute sclerosing panencephalitis is caused by a prion.

A) True
B) False

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False

Cryptococcal meningitis is highly communicable among humans.

A) True
B) False

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Each of the following is true for Listeria monocytogenes except


A) resistant to cold.
B) fastidious.
C) resistant to heat.
D) resistant to salt.
E) can result in septicemia.

F) B) and E)
G) A) and C)

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Some cases of CJD may be caused by a mutation of the PrP gene.

A) True
B) False

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Cryptococcus neoformans is a


A) virus.
B) bacteria.
C) prion.
D) fungus.
E) helminth.

F) A) and D)
G) A) and C)

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Meningococcemia is


A) best treated with ceftriaxone or aztreonam.
B) associated with vascular collapse,hemorrhage,and petechiae.
C) started from a nasopharyngeal infection.
D) caused by a gram-negative diplococcus.
E) All of the choices are correct.

F) B) and D)
G) B) and E)

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Viral meningitis normally requires aggressive antiviral treatment.

A) True
B) False

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Please read the clinical scenario, and then answer the question that follow to become familiar with the traditional NCLEX question format. Nancy has brought in her 75-year-old mother, Leah, into your ER because she has not been acting like herself. She has been using her hands less and less, complained of a severe headache, and then developed a severe tremor, high fever, and has now stopped talking. Her gait has also been effected. She reports a recent trip to the woods to go camping as a family. As Nancy is giving you the history, Leah collapses on the floor and has a seizure. -Multiple tests are performed,and it is discovered that Leah has Eastern equine encephalitis.What is the best initial treatment regimen?


A) acyclovir,hydration,antiepileptic drugs,LP
B) LP,CT,MRI
C) acyclovir,medical coma,heart catheterization
D) hydration,antiepileptic drugs,rapid cooling,neurosurgery consult

E) All of the above
F) A) and C)

Correct Answer

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Which of the following pertains to both tetanus and foodborne botulism?


A) occurs when spore-contaminated soil enters deep wounds
B) caused by enterotoxins of the pathogen
C) exotoxin blocks acetylcholine release
D) nausea and diarrhea are symptoms
E) treatment involves antitoxin therapy

F) B) and D)
G) C) and E)

Correct Answer

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Production of a neurotoxin that binds to target sites on spinal cord neurons responsible for inhibiting skeletal muscle contraction is a characteristic of


A) Clostridium botulinum.
B) Clostridium perfringens.
C) Clostridium difficile.
D) Clostridium tetani.
E) All of the choices are correct.

F) A) and B)
G) None of the above

Correct Answer

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Which of the following is not a causative agent of acute encephalitis?


A) JC virus
B) West Nile virus
C) herpes simplex virus
D) Toxoplasma gondii
E) California encephalitis

F) A) and D)
G) B) and D)

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Please read the clinical scenario, and then answer the question that follow to become familiar with the traditional NCLEX question format. Amanda is a 20-year-old college student who lives on campus. Her roommate brought her into your emergency room, because Amanda is not acting like herself. She was previously healthy, very involved in campus politics, and a 4.0 student. About 2 weeks ago, she started not feeling well. She had bad nasal congestion, and was diagnosed with a sinus infection. However, she decided against taking antibiotics because she did not believe they were good for her. She started getting very high fevers, which Amanda told her roommate were good because they were killing the infection. Yesterday, she started complaining of a stiff neck, and today she seems especially lethargic with a fever of 105. Her roommate was scared, so she forced her into her car and has driven her to your ICU. -What would have been the best way for Amanda to prevent getting this strand of meningitis?


A) not live in a college dormitory
B) take antibiotics with every cold
C) be vaccinated with Pneumovax
D) drink plenty of fluids

E) A) and C)
F) All of the above

Correct Answer

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C

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